Adiponectin is a protein hormone produced and secreted exclusively by adipocytes, or fat cells. It regulates the metabolism of fats and glucose and influences the body's response to insulin. Adiponectin has also been found to have anti-inflammatory effects on the cells lining the walls of blood vessels.

High blood levels of adiponectin are associated with a reduced risk of heart attack. Low levels of adiponectin are found in people who are obese (and who are at increased risk of a heart attack).

References

KK.Adiponectin and cardiovascular disease: response to therapeutic interventions.J Am Coll Cardiol. 2007 Feb 6;49(5):531-8. Epub 2007 Jan 19.Pischon T, Girman CJ, Rifai N, Hotamisligil GS, Rimm EB.Association between dietary factors and plasma adiponectin concentrations in men.Am J Clin Nutr. 2005 Apr;81(4):780-6. Spranger J, Mohlig M, Wegewitz U, Ristow M, Pfeiffer AF, Schillt T, Schlosser HW, Brabant G, Schofl C.Adiponectin Is Independently Associated With Insulin Sensitivity in Women With Polycystic Ovary Syndrome.Obstet Gynecol Surv. 2005 Apr;60(4):237-239.