The endocrine system is an integrated system of small organs that involve the release of extracellular signaling molecules known as hormones. The endocrine system is instrumental in regulating metabolism, growth, development and puberty, tissue function, and also plays a part in determining mood.

Like the nervous system, the endocrine system is an information signaling system. However, the nervous system uses nerves to conduct information, whereas the endocrine system mainly uses blood vessels as information channels. Glands located in many regions of the body release into the bloodstream specific chemical messengers called hormones. Hormones regulate the many and varied functions of an organism, e.g., mood, growth and development, tissue function, and metabolism, as well as sending messages and acting on them.

Endocrine glands include the pituitary, thyroid, and adrenal glands.

Diseases of the endocrine system are common, including diseases such as diabetes mellitus, thyroid disease, and obesity.

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